Ilkeston-born soapstar William Roache has been charged with five counts of indecent assault involving four girls aged 12 to 16 in the 1960s.
Mr Roache, 81, already faces two counts of rape involving a 15-year-old girl in Lancashire in 1967.
The latest charges relate to a period between 1965 and 1968, when the assaults are alleged to have been committed in the Manchester area.
He is due at Preston Magistrates Court on Friday.
The Crown Prosecution Service (CPS) said three of the alleged offences took place in 1965 and two in 1968.
Chief crown prosecutor for CPS North West Nazir Afzal said: “We have carefully considered all the evidence gathered by Lancashire Police in relation to recent allegations from four complainants that William Roache indecently assaulted them in the 1960s.
“We have concluded that there is sufficient evidence and it is in the public interest for Mr Roache to be charged with five offences of indecent assault relating to four girls who were aged between 11 or 12 and 16 at the time that the alleged offences happened.”
He said the allegations were made to police after Mr Roache was charged with the two offences of rape on May 1.
Mr Roache is due to appear at Preston Crown Court in relation to that case on Monday.